UpToDate AI and new tools
Posted: January 22, 2026
We are excited to announce that UpToDate AI Expert (also referred to as UpToDate AI) officially launched on Monday, Jan. 5. AI Expert is a new GenAI-powered tool grounded strictly in UpToDate’s trusted, evidence-based content. Designed by clinicians for clinicians, this innovation allows you to tap into the expertise of over 7,600 contributors in real time, answering complex questions with clear rationales and source citations. This new era of clinical support is designed to help you make faster, more confident decisions at the point of care. Alongside this launch, we are introducing (and reintroducing) several powerful UpToDate features.
Kidney Dosing Tool:
Prescribing for patients with renal impairment is now safer and more efficient with the Kidney Dosing Tool. It provides quick, expert-reviewed guidance across multiple medications and complex dialysis modalities, including intermittent hemodialysis, peritoneal dialysis, CRRT, PIRRT, and SLED. It is developed by a global panel of nephrology-focused PharmDs and clinicians and even includes augmented renal clearance data for critically ill patients.
Rx Transitions for Mental Health:
Switching antidepressants can be a delicate process. This tool provides step-by-step, personalized guidance to help clinicians safely transition medications while minimizing the risk of adverse reactions or loss of symptom control. Clinicians can select specific medications, doses, and transition speeds to tailor the plan to your patient’s unique needs.
Lab Interpretations:
When abnormal results raise questions, the Lab Interpretation monographs enable you to interpret findings more quickly and accurately, helping you decide on the next clinical steps with confidence.
UpToDate Pathways:
These are interactive guides designed to help you navigate specific clinical questions. They provide evidence-based recommendations synthesized exclusively from UpToDate content, society guidelines, and the latest medical literature.
We hope you enjoy exploring these new tools and testing out the UpToDate Expert AI. Please contact your liaison librarian or libaz@atsu.edu for any further questions or assistance.