Kirksville College of Osteopathic Medicine
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Neil J. Sargentini, PhD


Professor and Chair
Department of Microbiology and Immunology



Address: A.T. Still University of Health Sciences
Kirksville College of Osteopathic Medicine
800 W. Jefferson St.
Kirksville, MO  63501

PhD: Medical Microbiology, Stanford University, 1980


MA: Microbiology, California State University-Fresno, 1983


BS: Zoology, California State University-Fresno, 1969

Research: Senior Research Associate/ Asst. Lab Director: Stanford University, Dept. of Radiation Oncology, Radiobiology Research Division, 1980-1991

Research Interests: Dr. Sargentini's long-term research goal is to understand the molecular basis of DNA repair and mutagenesis in the bacterium Escherichia coli as a model for understanding the basis of cancer in humans. Presently, he is involved in characterizing the structure and function of RadA protein. Dr. Sargentini participated in the discovery of the radA gene and now is trying to determine its role in DNA repair. His other main research focus has been gamma radiation mutagenesis and how radiation chemistry, DNA damage, DNA repair processes, and translesion DNA replication interact to produce the mutations that are observed. Mutation analysis has involved the DNA sequencing of lacI forward mutations and long deletions within a lacI-Z fusion target.

List of Publications
Annual lists of Publications, Grants, Abstracts/Presentations and Honors for the ATSU/KCOM faculty are available under Scholarly Activity