Kirksville College of Osteopathic Medicine
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Publications of Pundurangan Ramaraj, PhD

   
13. Ramaraj P. In-vitro inhibition of human melanoma (BLM) cell growth by progesterone receptor antagonist RU-486 (Mifepristone). J Cancer Therapy, 2016;7:1045-1058. Link 
12. Leder DC [student], Brown JR, Ramaraj P. In-vitro rescue and recovery studies of human melanoma (BLM) cell growth, adhesion and migration functions after treatment with progesterone. Int J Clin Exp Med 2015;8(8):12275-12285. PDF.
11. Cox  JL, Chang Y, Ramaraj P. In-Vitro determination of biological and anabolic functions of weak androgen dehydroepiandrosterone (DHEA) using a variety of cell lines. Open J Endocr Metab Dis, 20155(8) 105-116. (Link to paper)
10

Ramaraj P, Artaza JN, Sinha-Hikim I, Taylor WE. Effect of androstenedione on adipogenesis in murine C3H10T1/2 mesenchymal cells. Open J Endocrin Metab Dis, 2015, 5, 9-18. Paper

9. Ramaraj P, Cox JL. In vitro effect of progesterone on human melanoma (BLM) cell growth. Int J Clin Exp Med. 2014 Nov 15;7(11):3941-53. eCollection 2014. PubMed. Paper
8. Ramaraj P, Cox J. In-vitro effect of sex steroids on mouse melanoma (B16F10) cell growth. CellBio, 2014. 3(2):60-71. doi: 10.4236/cellbio.2014.32007 Paper
7.
Jasuja R, Ramaraj P, Mac RP, Singh AB, Storer TW, Artaza J, Miller A, Singh R, Taylor WE, Lee ML, Davidson T, Sinha-Hikim I, Gonzalez-Cadavid N, Bhasin S. Delta-4-androstene-3,17-dione binds androgen receptor, promotes myogenesis in vitro, and increases serum testosterone levels, fat-free mass, and muscle strength in hypogonadal men. J Clin Endocrinol Metab. 2005 Feb;90(2):855-63. Epub
2004 Nov 2. PubMed
6.

Ramaraj P, Singh H, Niu N, Chu S, Holtz M, Yee JK, Bhatia R. Effect of mutational inactivation of tyrosine kinase activity on BCR/ABL-induced abnormalities in cell growth and adhesion in human hematopoietic progenitors. Cancer Res. 2004 Aug 1;64(15):5322-31. PubMed

5.
Ramaraj P, Rao AJ. Studies on LH modulated 8kDa peptide involved regulation of testosterone production in rat Leydig cells. Asian J Androl. 1999 Dec;1(4):191-4. PubMed
4.
Ramaraj P, Rao AJ. Regulation of an 8-kDa peptide involved in testosterone production by luteinizing hormone in rat Leydig cells. Biochem Mol Biol Int. 1999 May;47(5):857-63. PubMed
3.
Ramaraj P, Kessler SP, Colmenares C, Sen GC. Selective restoration of male fertility in mice lacking angiotensin-converting enzymes by sperm-specific expression of the testicular isozyme. J Clin Invest. 1998 Jul 15;102(2):371-8. PubMed
2.
Ghosh A, Desai SY, Sarkar SN, Ramaraj P, Ghosh SK, Bandyopadhyay S, Sen GC. Effects of mutating specific residues present near the amino terminus of 2'-5'-oligoadenylate synthetase. J Biol Chem. 1997 Jun 13;272(24):15452-8. PubMed
1.
Ramaraj P, Subbarayan VS, Rao JA. A possible role for a low molecular weight peptide in regulation of testosterone production by rat Leydig cells. Indian J Biochem Biophys. 1991 Oct-Dec;28(5-6):536-40. PubMed
A.
Thesis: Studies on the role of LH and LH modulated peptide factor in the regulation of testosterone production by rat Leydig cell
Books, Book Chapters, Reviews Return to top
2.

Ramaraj P. 2017. In-Vitro Inhibition of Melanoma Cell Growth and Viability by Progesterone – An Off-Target Protective Function, Chapter 3. In: Progesterone: Functions, Uses and Research Insights, (C. Rivera, ed), Nova Science Publishers, Hauppauge, NY. Link

1.
Ramaraj P. 2017. In-Vitro Anti-Cancer Actions of Progesterone on Human Melanoma Cells based on Recused and Recovered Cell Growth, Adhesion and Migration Functions, Chapter 2. In: Advances in medicine and biology, 113, (L.V. Berhardt, ed), Nova Science Publishers, Hauppauge, NY. Link
   
Poster Presentations/Published Abstracts Return to top

2016

Hohenbery T [student], Joshi K, Ramaraj P. In-Vitro Determination of Differential Roles of Androgens (Androstenedione and Testosterone) and Progesterone in Increased Male Mortality in Melanoma Using a Human Melanoma (BLM) Cell Model. Poster presented at the 98th annual Endocrine Society meeting; Boston, MA; April 1-4, 2016. Abstract

2016

Hohenbery T, Miller A, Ramaraj P. In-Vitro Determination of the Biological Bases for Increased Male Mortality in Melanoma Based on Mouse and Human Melanoma Cell Models. Poster presented at the 8th Annual Interdisciplinary Biomedical Research Conference; Kirksville, MO; November 5, 2016. 

2016

McGarvey T, Ramaraj P, Hassan SS. Vitamin K2 Prevents Beta Amyloid Peptide and Vitamin K3-induced Cell Death. Poster presented at Experimental Biology meeting, San Diego, CA; April 2-6, 2016. Abstract was published in FASEB Journal, April 2016, vol. 30 no. 1 Supplement 561.4

2016

Ramaraj P.  Steroids in Women Health, Steroids and Cancer, Corticosteroids and Anabolic Steroids and Supplements. Session Chair at the 2nd Global Summit on Hormones & Endocrine Disorders; New Orleans, LA; June 28, 2016

2016

Ramaraj P. Differential Effects of Dehydroepiandrosterone (DHEA) between Mouse and Human Melanoma Cell Lines. Oral lecture at the 2nd Global summit on Hormones & Endocrine Disorders; New Orleans, LA June 28, 2016. Abstract has been published in J Steroids Hormon Sci 2016, 7:2 (suppl), P-42 Abstract 

2016

Ramaraj P. In-vitro Determination of the Protective Function of Progesterone in Melanoma using Mouse and Human Melanoma Cell Models. Keynote lecture at the 2nd Global Summit on Hormones & Endocrine Disorders; New Orleans, LA; June 27, 2016. Abstract published in J Steroids Hormon Sci 2016, 7:2 (suppl), P-24 Abstract 

2016

Ramaraj P. Melanoma, Carcinoma, Melanoma & Carcinoma: Diagnosis. Session Chair at the Global Summit on Melanoma & Carcinoma; Brisbane, Australia, July 14-15, 2016.

2016

Ramaraj P. In-Vitro Determination of the Protective Function of Progesterone and its Receptor Antagonist RU-486  in Melanoma Using a Human Melanoma (BLM) Cell Model. Keynote talk the Global summit on Melanoma & Carcinoma at Brisbane, Australia, July 14-15, 2016. Abstract was published in J Cancer Sci Ther 2016, 8:6(suppl); DOI: 10.13140/RG.2.1.4238.7445. Link

2015

Baer R, Ramaraj P, Cox J, Cleaver LFour talks: Signaling Disruption in Melanoma (Baer R); Difference between Males and Females in Melanoma (Ramaraj P); Progress in Melanoma Therapies (Cox J); Clinical Trials and Clinical Case Discussion (Cleaver L). Oral presentations at the 1st Melanoma Symposium, ATSU-KCOM; Kirksville, MO, May 15, 2015.

2015

Hohenbery T [student], Le P [student], Badheka S [student], Ramaraj P. In-Vitro Determination of the Differential Roles of Androgens (Androstenedione and Testosterone) and Progesterone in Increased Male Mortality in Melanoma Using a Human Melanoma (BLM) Cell Model. Poster presented at the 7th Annual Interdisciplinary Biomedical Research Conference; Kirksville, MO; October 31, 2015.

2015

Joshi K [student], Ramaraj P*. Comparison of in-vitro effects of dehydroepiandrosterone (DHEA) between mouse and human melanoma cell lines. Poster presented at: 97th Annual Meeting of the Endocrine Society; March 5-8, 2015; San Diego, CA. Abstract published in: Endocr Rev. 2015;36(2 suppl):THR-286.

2015

Ramaraj P. Effect of Progesterone and its Receptor Antagonist RU-486 on Melanoma Cell Growth. Presented at the Global Steroid Summit; July 13-15, 2015; Baltimore, MD; and published as meeeting proceedings in Steroids Hormon Sci. 2015, 6:3, pp 44.

2015

Ramaraj P. In-Vitro Anti-Cancer Actions Progesterone on Human Melanoma (BLM) Cells, Based on Rescue and Recovery Studies of Cell Growth, Adhesion and Migration Functions. Invited talk at the 9th Indo Global Summit on Cancer Therapy; Hyderabad, India, November 2, 2015. Abstract is published in J Cancer Sci Ther 2015, 7 (10), P-36. http://dx.doi.org/10.4172/1948.5956.C1.054

2015

Ramaraj P. Is Melanoma a Hormone-Dependent Cancer? Invited Keynote lecture at the 9th Indo Global Summit on Cancer Therapy; Hyderabad, India, November 3, 2015. Abstract is published in J Cancer Sci Ther 2015, 7 (10), p-46. http://dx.doi.org/10.4172/1948-5956.C1.053

2015

Tasch J (student), Ramaraj P. In-Vitro Determination of Androgens (Androstenedione and Testosterone) Roles in Increased Male Mortality in Melanoma Using a Mouse Melanoma (B16F10) Cell Model. Poster presented at the 2015 American Society for Cell Biology annual meeting; San Diego, CA, Dec. 12-16, 2015; and published in Mol Biol of the Cell, 2015; 26(25): Doi:10.1091/mbc.E15-09-0674

2014

Leder DC [student], Joshi K [student], Ramaraj P.*  Rescued and recovered in-vitro functions of progesterone treated human melanoma (BLM) cells. Poster was presented at the 96th annual Endocrine Society meeting; Chicago, IL June 20-24, 2014. Abstract

2014

Leder DC [student], Ramaraj P. In-Vitro Rescue and Recovered Studies on Human Melanoma (BLM) Cell Growth, Adhesion and Migration Functions after Treatment with RU-486. Poster presented at the 2014 American Society for Cell Biology/ International Federation for Cell Biology Meeting; Philadelphia, PA; Dec 6-10, 2014. Abstract (P1150/B482) published in Mol. Biol. Cell. Dec. 15, 2014, vol. 25, no. 25, 3987; doi: 10.1091/mbc.E14-10-1437

2014

Leder DC [student], Ramaraj P. In-Vitro Rescue and Recovery Studies of Human Melanoma (BLM) Cell Growth, Adhesion and Migration Functions after Treatment with Mifepristone (RU-486). Poster presented at 6th Annual Interdisciplinary Biomedical Research Conference; Kirksville, MO; November 1, 2014.

2014

Ramaraj P. Effect of Progesterone and its Receptor Antagonist RU-486 on Melanoma Cell Growth. Invited talk at the Research Seminar, Dept. of Internal Medicine and Dept. of Health and Life Sciences, Charles Drew University of Medicine and Sciences, Los Angeles, CA; October 29, 2014

2013

Joshi K, Ramaraj P. Differential Effects of Dehydroepiandrosterone (DHEA) Between Mouse and Human Melanoma Cell Lines. Poster presented at 5th Annual Interdisciplinary Biomedical Research Conference; Kirksville, MO; November 2, 2013.

2013

Ramaraj P, Chang Y, Cox JL. In-Vitro Determination of Biological and Anabolic Functions of Weak Androgen Dehydroepiandrosterone (DHEA) Using a Variety of Cell Lines. Meeting abstract published at Endocrine Rev 2013; 34 (03_Meeting/Abstracts): SAT-352. Poster presented at the 95th annual Endocrine-Society Meeting; San Francisco, CA; June 15, 2013.

2012

Ramaraj P, Cox JL. Effect of Progesterone on Melanoma Cell Growth. Poster presented at the 94th Annual Meeting of The Endocrine Society, Houston, TX; June 23-26, 2012.

2012

Ramaraj P, Leder DC [student], Cox JL. Effect of Progesterone on In-Vitro Functions of Human Melanoma (BLM) Cells. Poster presented at 4th Annual Interdisciplinary Biomedical Research Conference; Kirksville, MO; September 29, 2012.

2012

Ramaraj P, Tasch J [student]. Effect of Androgens (DHEA, AD and T) on Mouse Melanoma Cell Growth. Poster presented at 4th Annual Interdisciplinary Biomedical Research Conference; Kirksville, MO; September 29, 2012.

2011

Ramaraj P, Cox JL. Effect of steroids on in-vitro melanoma cell growth and viability. Endocrine Reviews, 12 (3), P1-29 abstract, June 2011. Poster presentation at the 93rd annual endocrine society meeting at Boston, June 4-7, 2011

2011

Ramaraj P, Brown J [student], Cox JL. Effect of Progesterone Treatment on Melanoma Cell Growth and Adhesion. Poster presented at 3rd Annual Interdisciplinary Biomedical Research Conference; Kirksville, MO; October 22, 2011.

2010

Cox JL, Ramaraj P. Effect of mifepristone (RU-486) on in-vitro melanoma cell growth and viability Mol. Biol. Cell  21 (supplement) Abstract no. 655, December  2010; Poster presented at: 50th annual Society for Cell Biology meeting, Philadelphia, Dec 10-15, 2010

2010

Ramaraj P, Cox JL. Effect of Mifepristone (RU-486) on In-vitro Melanoma Cell Growth and Viability. Poster presented at 2nd Annual Interdisciplinary Biomedical Research Conference; Kirksville, MO; October 9, 2010.

2010

Ramaraj P, Artaza JN, Sinha-Hikim I, Taylor WE. Effect of Androstenedione on adipogenesis in an in-vitro bioassay using mouse mesenchymal multipotent C3H 10T1/2 cells; Endocrine Reviews, vol.31, No.(3), June 2010 supplement-1; Poster presentation   at the 92nd annual endocrine society meeting, San Diego, June 19-22, 2010