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Publications of Yingzi Chang, MD, PhD

42.
Tan X, Gao J, Shi Z, Tai S, Chan LL, Yang Y, Peng DQ, Liao DF, Jiang ZS, Chang YZ, Gui Y, Zheng XL. MG132 Induces Expression of Monocyte Chemotactic Protein-Induced Protein 1 in Vascular Smooth Muscle Cells. J Cell Physiol. 2016 Mar 31. doi: 10.1002/jcp.25396. [Epub ahead of print] PubMed
41.
Holdaway BB (student), Moody JD (student), Brooks LF (student), Fu M, Kolattukudy P, Chang Y. MCPIP1 Deficiency Increases Insulin Sensitivity but Impairs Hepatic Insulin Signal Transduction in Mice. Jacobs J Diabetes Endocrinol. 2015 Nov 1(1). Paper
40.
Cox  JL, Chang Y, Ramaraj P. In-Vitro determination of biological and anabolic functions of weak androgen dehydroepiandrosterone (DHEA) using a variety of cell lines. Open J Endocr Metab Dis, 20155(8) 105-116. (Link to paper)
39.
White R, Holdaway BB, Moody JD, Chang Y. Chronic caffeine administration attenuates vascular injury-induced neointimal hyperplasia in rats. J Caffeine Res. 2013 Dec;3(4):163-168.
38.
Gan Y, Zhang Y, Buckels A, Paterson AJ, Jiang J, Clemens TL, Zhang ZY, Du K, Chang Y, Frank SJ. IGF-1R Modulation of Acute GH-Induced STAT5 Signaling: Role of Protein Tyrosine Phosphatase Activity. Mol Endocrinol. 2013 Nov;27(11):1969-79. doi: 10.1210/me.2013-1178. Epub 2013 Sep 12. PubMed
37.
Qi D, Huang S, Miao R, She ZG, Quinn T, Chang Y, Liu J, Fan D, Chen YE, Fu M. Monocyte Chemotactic Protein-induced Protein 1 (MCPIP1) suppresses stress granule formation and determines apoptosis under stress. J Biol Chem. 2011 Dec 2;286(48):41692-700. Epub 2011 Oct 4. PubMed
36.

Chang Y. A central role of PTP1B in hyperinsulinemia-enhanced IL-6 signaling in dedifferentiated vascular smooth muscle cells. J Diabet Metabol 2:118 (Mar. 4, 2011) Paper

35.
Pu Q, Chang Y, Zhang C, Cai Y, Hassid AI. Chronic insulin treatment suppresses PTP1B function, induces increased PDGF signaling and amplifies neointima formation in balloon injured rat artery. Am J Physiol Heart Circ Physiol. 2008 Nov 14. [Epub ahead of print] PubMed
34.
Zhuang D, Pu Q, Ceacareanu B, Chang Y, Dixit M, Hassid A. Chronic insulin treatment amplifies PDGF-induced motility in differentiated aortic smooth muscle cells by suppressing the expression and function of PTP1B. Am J Physiol Heart Circ Physiol. 2008 Jul;295(1):H163-73. Epub 2008 May 2. PubMed
33.
Chang Y, Ceacareanu B, Zhuang D, Zhang C, Pu Q, Ceacareanu AC, Hassid A. Counter-regulatory function of protein tyrosine phosphatase 1B in platelet-derived growth factor- or fibroblast growth factor-induced motility and proliferation of cultured smooth muscle cells and in neointima formation. Arterioscler Thromb Vasc Biol. 2006 Mar;26(3):501-7. Epub 2005 Dec 22. PubMed
32.
Ceacareanu AC, Ceacareanu B, Zhuang D, Chang Y, Ray RM, Desai L, Chapman KE, Waters CM, Hassid A. Nitric oxide attenuates IGF-I-induced aortic smooth muscle cell motility by decreasing Rac1 activity: essential role of PTP-PEST and p130cas. Am J Physiol Cell Physiol. 2006 Apr;290(4):C1263-70. Epub 2005 Dec 14. PubMed
31.
Chang Y, Lawson LJ, Hancock JC, Hoover DB. Pituitary adenylate cyclase-activating polypeptide: localization and differential influence on isolated hearts from rats and guinea pigs. Regul Pept. 2005 Jul 15;129(1-3):139-46. PubMed
30.
Chang Y, Zhuang D, Zhang C, Hassid A. Increase of PTP levels in vascular injury and in cultured aortic smooth muscle cells treated with specific growth factors. Am J Physiol Heart Circ Physiol. 2004 Nov;287(5):H2201-8. Epub 2004 Jul 22. Erratum in: Am J Physiol Heart Circ Physiol. 2006 Apr;290(4):H1727. PubMed
29.
Chang Y, Ceacareanu B, Dixit M, Sreejayan N, Hassid A. Nitric oxide-induced motility in aortic smooth muscle cells: role of protein tyrosine phosphatase SHP-2 and GTP-binding protein Rho. Circ Res. 2002 Sep 6;91(5):390-7. PubMed
28.
Chang Y, Stover SR, Hoover DB. Regional localization and abundance of calcitonin gene-related peptide receptors in guinea pig heart. J Mol Cell Cardiol. 2001 Apr;33(4):745-54. PubMed
27.
Hoover DB, Chang Y, Hancock JC, Zhang L. Actions of tachykinins within the heart and their relevance to cardiovascular disease. Jpn J Pharmacol. 2000 Dec;84(4):367-73. Review. PMID: 11202607 PubMed
26.
Chang Y, Hoover DB, Hancock JC, Smith FM. Tachykinin receptor subtypes in the isolated guinea pig heart and their role in mediating responses to neurokinin A. J Pharmacol Exp Ther. 2000 Jul;294(1):147-54. PubMed
25.
Chang Y, Hoover DB, Hancock JC. Endogenous tachykinins cause bradycardia by stimulating cholinergic neurons in the isolated guinea pig heart. Am J Physiol Regul Integr Comp Physiol. 2000 Jun;278(6):R1483-9. PubMed
24.
Hoover DB, Chang Y, Hancock JC. Characterization of responses to neurokinin A in the isolated perfused guinea pig heart. Am J Physiol. 1998 Dec;275(6 Pt 2):R1803-11. PMID: 9843869 PubMed
23.
Liu NK, Li CW, Zhao D, Ren XY, Chang YZ, Tang CS, Su JY. Effects of L-arginine and taurine on vascular smooth muscle cell proliferation after balloon catheter-induced vascular injury. Chin J. Pathophysiol. 1997;13(3):286-9.
22.
Zhang LZ, Chang YZ, Liu NK, Pang YZ, Gao AG, Su JY, Tang CS. Association of myocardial NA+-K+-ATPase activity and heart functions in rat septic shock. Chin J. Pathophysiol. 1997;13(3):240-4.
21.
Zhou L, Chang YZ, Qiu ZY, Piao H, Liu CF, Tang CS. Protective role of bFGF on ischemia/reperfusion-induced myocardial injury in isolated rat hearts. Basic Med Sci Clin. 1997;17(4):33-5.
20.
Chang YZ, Tang CS. Changes of adrenoceptors in shock (Review). Basic Med Sci Clin. 1997;17(4):15-9.
19.
Yang HP, Gao AG, Dong LW, Chang YZ, Wu LL, Tang CS. Studies on changes and its mechanisms of hepatocellular sarcolemmal α1-AR during rat septic shock. Basic Med. Sci Clin. 1997;17(2):108-14.
18.
Shabotofu D, Wang XH, Chang YZ, Zhang LZ, Liu XH, Tang CS. Protective role of cGRP on endothelium balloon denudation of rat aorta. J Chin Atheroscler. 1997;5(2):103-6.
17.
Chang YZ, Ye C, Zhou L, Chen K, Pang YZ, Tang CS. Changes of myocardial sarcolemmal vesicle Na+-Ca2+ exchanger in hypertensive rats induced by L-NNA. J. Beijing Med Univ. 1997;29(1):32-4.
16.
Yang J, Zhao D, Chang YZ, Tian Q, Zhao YT, Shi XY, Zhang ZK, Tang CS. Protective role of adrenomedullin (13-52) on isoproterenol-induced myocardial injury in rats. Chin Pharmacol. Bull. 1996;12(6):530-2.
15.
Chang YZ, Gao AG, Wu LL, Su JY, Tang CS, Liu MS. Changes of myocardial muscarinic receptor during septic shock of the rat. ACTA Biochimca et Biophysica Sinica. 1996;28(5):485-491. PubMed
14.
Chang YZ, Gao LR, Lu XY, Zhao YT, Su JY, Tang CS. Lactate transportation disturbance in SHR myocardium. Chin J. Hypertens. 1996;4(3):191-3.
13.
Liu XH, Pang YZ, Chang YZ, Su JY, Tang CS. Ischemic preconditioning protects intestine against ischemia reperfusion injury by protein kinase activation. J. Beijing Med Univ. 1996;28(2):86-8.
12.
Ye C, Wang JX, Chang YZ, Song HS, Liu XH, Tang CS. Effects of anoxia-reoxygenation on taurine transfer rabbit aortic smooth muscle cells. J. Beijing Med Univ. 1996;28(6):422-4.
11.
Liu NK, Chang YZ, Cen LZ, Su JY, Tang CS. The role of Ca2+ homeostasis imbalance in endothelial balloon denudation-induced vascular smooth muscle cell proliferation. J Chin Med. 1996;76(4):297-300.
10.
Ye C, Chang YZ, Tang CS, Wang JX, Liu LY. Effects of anoxia-reoxygenation on taurine transfer in rat spinal cord. Basic Med Sci Clin. 1996;16(5):44-6.
9.
Chang YZ, Su JY. Sensitivity of Ca2+-overloaded rat myocardium toward ischemia/reperfusion- and oxygen free radical-induced injury. Chin J Pathophysiol. 1996;12(4):399-401.
8.
Chang YZ, Su JY. Protective role of 654-2 on rat myocardial ischemia/reperfusion-induced injury. Basic Med Sci and Clin. 1995;15(2):28-31.
7.
Chang YZ, Su JY. Effect of different concentrations of calcium in preperfusion buffer on calcium regulation in rat myocardial mitochondria. J Beijing Med Univ. 1995;27(supple):15-6.
6.
Dong LW, Chang YZ, Tong LJ, Tang J, Su JY, Tang CS. Role of regulatory peptide in pathogenesis of shock. Sci China B. 1994 Feb;37(2):162-9. PubMed
5.
Chang YZ, Su JY. Pathogenesis of myocardial ischemia/reperfusion-induced injury (Review). Basic Med. Sci. Clin. 1993;13(1):16-20.
4.
Chang YZ, Su JY. Effect of different concentrations of calcium in reperfusion buffer on ischemia/reperfusion-induced injury in isolated rat hearts. J Beijing Med Univ. 1993;25(5):335-7.
3.
Chang YZ, Su JY. Effect of different concentrations of calcium in reperfusion buffer on mitochondrial Ca2+-uptake and calcium contents in rat myocardium. Chin Sci Bull. 1993;38(12):1125-7.
2.
Cheng S, Chang YZ, Wang DY, Hua Y. Quenching effect of MT on free radical signal during myocardial ischemia/reperfusion-induced injury. J Chin Med. 1992;72(12):749-51.
1.
Chang YZ, Liang DQ. Protective role of DS-182 in the H+-ATPase activity of rat myocardial mitochondria against free radical damage. Chin J Pathophysiol. 1991;7(5):449-52.
   
Poster Presentations/Published Abstracts Return to top

2016

Chen RA, Chang Y. Role of MCPIP1 in High Insulin-Related Endothelial Cell Dysfunction. Poster presented at the 8th Annual Interdisciplinary Biomedical Research Conference; Kirksville, MO; November 5, 2016.

2016

Yang CChang Y. Age-related Lipid Profiles Changes in MCPIP1 Deficient Mice. Poster presented at the 8th Annual Interdisciplinary Biomedical Research Conference; Kirksville, MO; November 5, 2016.

2015

Naik C [student]*, Chang Y. Possible role of MCPIP1 in insulin-enhanced vascular injury-induced restenosis. Poster presented at: Experimental Biology 2015; March 28-April 1, 2015; Boston, MA. Abstract published in: FASEB J. 2015;29(1 suppl):782.9.

2015

Sedinkin J [alum]*, Chang Y. Mechanism of impaired lipid homeostasis in MCPIP1-deficient mice. Poster presented at: Experimental Biology 2015; March 28-April 1, 2015; Boston, MA. Abstract published in: FASEB J. 2015;29(1 suppl):1020.3.

2014

Naik CY [student], Chang Y. Possible Role of MCPIP1 in Insulin-Enhanced Vascular Injury-Induced Restenosis. Poster presented at 6th Annual Interdisciplinary Biomedical Research Conference; Kirksville, MO; November 1, 2014.

2014

Naik CY [student], Chang Y. Role of MCPIP1 in Insulin-Induced Migration and Proliferation in Vascular Smooth Muscle Cells. Poster presented at the 3rd Annual Missouri Osteopathic Student and Post-graduate Research Symposium; Missouri Osteopathic Annual Convention; Branson, MO; April 30-May 4, 2014.

2014

Sedinkin JD [student], Chang Y. Role of MCPIP1 in Controlling Hepatic Lipid Handling. Poster presented at the 3rd Annual Missouri Osteopathic Student and Post-graduate Research Symposium; Missouri Osteopathic Annual Convention; Branson, MO; April 30-May 4, 2014; and at 6th Annual Interdisciplinary Biomedical Research Conference; Kirksville, MO; November 1, 2014.

2013

Chang Y, Holdaway BB [student], Moody JD [student], Fu M, Kolattukudy P. MCPIP-1 Deficiency Induces Hepatic Inflammation and Impairs Insulin Signaling in Mice. FASEB J April 9, 2013 27:918.5

2013

Holdaway BB [student], Naik CY [student], Chang Y. Insulin-Induces Adipogenesis in Immortalized MEF Cells. Poster presented at 5th Annual Interdisciplinary Biomedical Research Conference; Kirksville, MO; November 2, 2013.

2013

Moody J [student], Sedinkin J [student], Chang Y. The role MCPIP-1 in Maintaining Lipid Homeostasis. Poster presented at 5th Annual Interdisciplinary Biomedical Research Conference; Kirksville, MO; November 2, 2013.

2013

Ramaraj P, Chang Y, Cox JL. In-Vitro Determination of Biological and Anabolic Functions of Weak Androgen Dehydroepiandrosterone (DHEA) Using a Variety of Cell Lines. Meeting abstract published at Endocrine Rev 2013; 34 (03_Meeting/Abstracts): SAT-352. Poster presented at the 95th annual Endocrine-Society Meeting; San Francisco, CA; June 15, 2013.

2012

White R [student], Chang Y. The Effects of Caffeine on Vascular Injury-Induced Neointimal Hyperplasia. (Poster presentation). Experimental Biology 2012, San Diego, CA. April 23, 2012

2011

Chang Y*. A Central Role of PTP1B in Hyperinsulinemia-enhanced IL-6 Signaling in Vascular Smooth Muscle Cells. Presented at: Experimental Biology 2011; Washington, DC; April 9-13, 2011.

2011

White RD [student], Chang Y. The Effects of Caffeine on Vascular Injury-induced Neointimal Hyperplasia. Poster presented at 3rd Annual Interdisciplinary Biomedical Research Conference; Kirksville, MO; October 22, 2011.

2010

Quinn NR [student], White RD [student], Chang Y. Effect of Simvastatin on Vascular Induced Neointimal Formation. Poster presented at 2nd Annual Interdisciplinary Biomedical Research Conference; Kirksville, MO; October 9, 2010.

2010

White RD [student], Quinn NR [student], Chang Y. Development of Suitable Sample Lysis Buffers for Use in ELISA. Poster presented at 2nd Annual Interdisciplinary Biomedical Research Conference; Kirksville, MO; October 9, 2010.

2009

Gaffney J [student], Theobald RJ, Chang Y; Calcium flux in urinary bladder smooth muscle cells; Presented at the 1st Annual Interdisciplinary Biomedical Research Symposium; A.T. Still University of Health Sciences; Kirksville, MO; Sept. 26, 2009.