Master of Biomedical Sciences (M.S.)

FACULTY MEMBERS

RESEARCH TOPICS

Peter Kondrashov, Ph.D.

pkondrashov@atsu.edu

660-626-2771

Musculoskeletal adaptations to various modes of locomotion

Microstructure of bone using scanning electron microscopy

Edwin Purcell, Ph.D.

epurcell@atsu.edu

660-626-2217

Neural influences on immune function

Effect of osteopathic manipulation on autonomic function

Diana Rhodes, Ph.D.

drhodes@atsu.edu

660-626-2149

James Rhodes, Ph.D.

60-626-2753

Cell-cycle kinetics, in vivo, using mouse skin as a model with the long-term goal of understanding how tissues regulate their size

Role of protease and glycosidase activities in human urine and association with interstitial cystitis

Biochemistry Department

James Cox, Ph.D.

jcox@atsu.edu

660-626-2466

Gene studies in cancer

Proteases in tumor metastasis

Richard Fleschner, Ph.D.

cfleschner@atsu.edu

660-626-2761

Biochemistry of ocular lens plasma membranes

Identification and quantification of various intrinsic and extrinsic proteins associated with various ocular lens membrane fractions using one- and two-dimensional electrophoresis and western blotting

Microbiology and Immunology Department

Neal Chamberlain, Ph.D.

nchamberlain@atsu.edu

660-626-2474

Mechanisms of pathogenicity of Staphylococcus aureus and S. epidermidis

Mechanisms of antibiotic survival of S. epidermidis in biofilms

Neil Sargentini, Ph.D.

nsargentini@atsu.edu

660-626-2474

Genetic regulation associated with osteopathic manipulative medicine in a rat model for nociceptive pain

Effect of DNA repair protein RadA on global gene expression in E. coli

Genetic analysis of culture medium-dependent repair in x-irradiated Escherichia coli

Genetic control of UV radiation mutagenesis in Escherichia coli

Vineet Singh, Ph.D.

vsingh@atsu.edu

660-626-2474

Molecular mechanisms of antibiotic and stress tolerance in Staphylococcus aureus

Molecular mechanisms of Staphylococcus aureus pathogenesis 

Melissa Stuart, Ph.D.

mstuart@atsu.edu

660-626-2474

Monoclonal antibody production, biochemical characterization of proteins

Identification of a 61 kD protein involved in eukaryotic protein synthesis

Identification of a 14-18 kD rat lens protein that may be involved in cataract formation

Pharmacology Department

Yingzi Chang, Ph.D.

ychang@atsu.edu

660-626-2327

Mechanisms of insulin-enhanced restenosis after angioplasty in type II diabetes

Interaction between insulin and TNF-α on vascular injury-induced neointima formation

Involvement of protein tyrosine phosphatase 1B in insulin-enhanced vascular injury-induced neointima formation

John Martin, Ph.D.

jmartin@atsu.edu

660-626-2384

Interaction between NPY and PYY microinjected into the PHN on blood pressure and heart rate using isobolograms

Effect of cannabinoids on the release (or efflux) of the neurotransmitter acetylcholine from cholinergic nerve terminals of the posterior hypothalamic nucleus

Signal transduction mechanisms in the posterior hypothalamic nucleus – differences in receptors stimulated by the related peptides NPY and PYY, and their potential interaction with the responses evoked by agents that mimic acetylcholine

Involvement of the posterior hypothalamic nucleus in reflex-mediated responses to hemorrhage in conscious rats.

Functional adaptational changes of the central serotonin (5-HT)2A receptor caused by the 5-HT2A/2C receptor agonist DOI

Involvement of the enzyme GSK-3 in changes in behaviors evoked by dopamine agonists that occur during the development of tolerance and dependence to opioids

David Middlemas, Ph.D.

dmiddlemas@atsu.edu

Neuropharmacology of brain derived neurotrophic factor (BDNF)

The role of brain derived neurotrophic factor (BDNF) and its receptor, TrkB, in drug action

The role of neurogenesis in anti-depressant drug action

Robert Theobald, Ph.D.

rtheobald@atsu.edu

Autonomic smooth muscle pharmacology of the lower urinary tract of the cat; particularly the roles of ATP, nitric oxide, hormones, and cannabinoid agents on the regulation of cat bladder smooth muscle function

Effect of cannabinoids in the periaqueductal gray (PAG) area on lower urinary tract function of the cat

Study of the role of estrogen in the lower urinary tract, and the interaction of estrogen with other regulatory agents

Physiology Department

Robert Baer, Ph.D.

rbaer@atsu.edu

Signal transduction in cellular adhesion and motility

Adhesion molecules in melanoma – migration, invasion, apoptosis

Signaling in vascular and vascular-like network formation (angiogenesis and vasculogenic mimicry)

George Carlson, Ph.D.

ccarlson@atsu.edu

Pathogenesis of muscular dystrophy – role of Ca2+ and NFkappaB

Developing new treatments for muscular dystrophy using drugs that modulate cell signaling pathways

Timothy Geisbuhler, Ph.D.

tgeisbuhler@atsu.edu

Impact of anoxia, estrogen, and phytoestrogens on NFkB in heart

Calcium traffic across heart cell membranes

Nucleotide metabolism in ischemic and anoxic heart cells (bioenergetics)

Impact of plant natural products (“nutritional supplements”) on cardiac cell metabolism

Fred Peterson, Ph.D.

fpeterson@atsu.edu

660-626-2309

Neural control of the circulation

Exercise-induced hypotension

William Sexton, Ph.D.

wsexton@atsu.edu

Determinants of oxygen delivery in the microcirculation of skeletal muscle, heart and diaphragm with emphasis on the impact of exercise training, diabetes, aging, and hypertension

Role of nitric oxide in the control of oxygen delivery and utilization in contracting skeletal muscle, diaphragm and heart and interactions with disease and aging

Diaphragm function in health and disease (e.g., emphysema and diabetes)

Molecular mechanisms of angiogenesis in skeletal muscle, diaphragm and heart